United States securities and exchange commission logo October 25, 2022 Terrence A. Duffy Chief Executive Officer CME Group Inc. 20 South Wacker Drive Chicago, Illinois 60606 Re: CME Group Inc. Definitive Proxy Statement on Schedule 14A Filed March 17, 2022 File No. 001-31553 Dear Terrence A. Duffy: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Disclosure Review Program